Neurochemistry

• Control of glutamate release by complexes of adenosine and cannabinoid receptors (24 Sep 2024)
  
• The Role of Cannabinoids in Allergic Diseases: Collegium Internationale Allergologicum (CIA) Update 2020 (16 Sep 2024)
  
• Different Effects of Cannabis Abuse on Adolescent and Adult Brain (16 Sep 2024)
  
• Chemical Characteristics, Therapeutic Uses, and Legal Aspects of the Cannabinoids of Cannabis sativa: A Review (16 Sep 2024)
  
• Hypothalamic cannabinoid signaling: Consequences for eating behavior (03 Sep 2024)
  
• Comparing CB1 receptor GIRK channel responses to receptor internalization using a kinetic imaging assay (03 Sep 2024)
  
• Cannabinoids and monoaminergic system: implications for learning and memory (03 Sep 2024)
  
• The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits (02 Sep 2024)
  
• The Relationship between Muscarinic and Cannabinoid Receptors in Neuronal Excitability and Epilepsy: A Review (02 Sep 2024)
  
• The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer’s Disease (02 Sep 2024)
  
• The Implications of Cannabinoid-Induced Metabolic Dysregulation for Cellular Differentiation and Growth (02 Sep 2024)
  
• The Impact of the CB2 Cannabinoid Receptor in Inflammatory Diseases: An Update (02 Sep 2024)
  
• The effect of cannabinoid type 2 receptor agonist on morphine tolerance (02 Sep 2024)
  
• Role of the CB2 Cannabinoid Receptor in the Regulation of Food Intake: A Systematic Review (02 Sep 2024)
  
• Research progress on the cannabinoid type-2 receptor and Parkinson’s disease (02 Sep 2024)
  
• Potential of CBD Acting on Cannabinoid Receptors CB1 and CB2 in Ischemic Stroke (02 Sep 2024)
  
• Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs (02 Sep 2024)
  
• Pharmacological Evaluation of Cannabinoid Receptor Modulators Using GRABeCB2.0 Sensor (02 Sep 2024)
  
• Interaction of Synthetic Cannabinoid Receptor Agonists with Cannabinoid Receptor I: Insights into Activation Molecular Mechanism (02 Sep 2024)
  
• Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists (02 Sep 2024)
  
• Exploring the Therapeutic Potential of Cannabinoid Receptor Antagonists in Inflammation, Diabetes Mellitus, and Obesity (02 Sep 2024)
  
• Editorial: Insights on cannabinoid translational science and medicine: the endocannabinoidome as a target for clinical practice (02 Sep 2024)
  
• Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors (02 Sep 2024)
  
• Classical cannabinoid receptors as target in cancer-induced bone pain: a systematic review, meta-analysis and bioinformatics validation (02 Sep 2024)
  
• Cannabinoid receptors type 2: Function and development in agonist discovery from synthetic and natural sources with applications for the therapy of osteoporosis (02 Sep 2024)
  
• Cannabinoid and Orexigenic Systems Interplay as a New Focus of Research in Alzheimer’s Disease (02 Sep 2024)
  
• Cannabinoid Analgesia in Postoperative Pain Management: From Molecular Mechanisms to Clinical Reality (02 Sep 2024)
  
• A Humanized CB1R Yeast Biosensor Enables Facile Screening of Cannabinoid Compounds (02 Sep 2024)
  
• A collection of cannabinoid-related negative findings from autaptic hippocampal neurons (30 Aug 2024)
  
• Role of neuronal nicotinic acetylcholine receptors in cannabinoid dependence ☆ (29 Aug 2024)
  
• Neuronal Cannabinoid CB1 Receptors Suppress the Growth of Melanoma Brain Metastases by Inhibiting Glutamatergic Signalling (29 Aug 2024)
  
• Editorial: Cannabinoid interactions with ion channels, receptors, and the bio-membrane (29 Aug 2024)
  
• Cannabinoid Receptor 1 Agonist ACEA and Cannabinoid Receptor 2 Agonist GW833972A Attenuates Cell-Mediated Immunity by Different Biological Mechanisms (29 Aug 2024)
  
• Cannabinoid and Opioid Receptor Affinity and Modulation of Cancer-Related Signaling Pathways of Machaeriols and Machaeridiols from Machaerium Pers. (29 Aug 2024)
  
• Understanding the Dynamics of the Structural States of Cannabinoid Receptors and the Role of Different Modulators (28 Aug 2024)
  
• The endocannabinoid systemʼs involvement in motor development relies on cannabinoid receptors, TRP channels, and Sonic Hedgehog signaling (28 Aug 2024)
  
• Role of Endo-opioid and Endo-cannabinoid Systems in Migraine and Medication-overuse Headache (28 Aug 2024)
  
• Microglial Cannabinoid CB2 Receptors in Pain Modulation (28 Aug 2024)
  
• Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases (28 Aug 2024)
  
• Voltage dependence of the cannabinoid CB1 receptor (27 Aug 2024)
  
• The Role of Cannabinoid Type 2 Receptors in Parkinson’s Disease (27 Aug 2024)
  
• The Enteric Glia and Its Modulation by the Endocannabinoid System, a New Target for Cannabinoid-Based Nutraceuticals? (27 Aug 2024)
  
• Synthetic cannabinoid WIN 55,212–2 inhibits growth and induces cell death of oral and pancreatic stem-like/poorly differentiated tumor cells (27 Aug 2024)
  
• Evaluation of cannabinoid receptors type 1–2 in periodontitis patients (27 Aug 2024)
  
• Cannabinoid CB2 Receptors in Neurodegenerative Proteinopathies: New Insights and Therapeutic Potential (27 Aug 2024)
  
• A Crosstalk between the Cannabinoid Receptors and Nociceptin Receptors in Colitis—Clinical Implications (27 Aug 2024)
  
• Role of Cannabinoid CB2 Receptor in Alcohol Use Disorders: From Animal to Human Studies (25 Aug 2024)
  
• Modulation of type 1 cannabinoid receptor activity by cannabinoid by-products from Cannabis sativa and non-cannabis phytomolecules (25 Aug 2024)
  
• Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits (25 Aug 2024)
  
• Cannabinoid signaling and risk in Huntington's disease (25 Aug 2024)
  
• Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration (25 Aug 2024)
  
• The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors (21 Aug 2024)
  
• Roles of the Cannabinoid System in the Basal Ganglia in Parkinson’s Disease (21 Aug 2024)
  
• Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death (21 Aug 2024)
  
• MD Simulations Revealing Special Activation Mechanism of Cannabinoid Receptor 1 (21 Aug 2024)
  
• Therapeutic potential of the cannabinoid receptor 2 in neuropsychiatry (20 Aug 2024)
  
• The Treatment of Cognitive, Behavioural and Motor Impairments from Brain Injury and Neurodegenerative Diseases through Cannabinoid System Modulation—Evidence from In Vivo Studies (20 Aug 2024)
  
• Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors (20 Aug 2024)
  
• Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products (20 Aug 2024)
  
• Protein Interactors and Trafficking Pathways That Regulate the Cannabinoid Type 1 Receptor (CB1R) (20 Aug 2024)
  
• Pros and Cons of the Cannabinoid System in Cancer: Focus on Hematological Malignancies (20 Aug 2024)
  
• Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review (20 Aug 2024)
  
• High Expression of Cannabinoid Receptor 2 on Cytokine-Induced Killer Cells and Multiple Myeloma Cells (20 Aug 2024)
  
• Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases (20 Aug 2024)
  
• Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity (20 Aug 2024)
  
• Cannabinoids and Cannabinoid Receptors: The Story so Far (20 Aug 2024)
  
• Cannabinoid Therapeutics in Chronic Neuropathic Pain: From Animal Research to Human Treatment (20 Aug 2024)
  
• Cannabinoid Signaling in Auditory Function and Development (20 Aug 2024)
  
• Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases (20 Aug 2024)
  
• Cannabinoid Receptor 1/miR-30b-5p Axis Governs Macrophage NLRP3 Expression and Inflammasome Activation in Liver Inflammatory Disease (20 Aug 2024)
  
• Cannabinoid pharmacology and its therapeutic uses in Alzheimer’s disease (20 Aug 2024)
  
• Cannabinoid Control of Olfactory Processes: The Where Matters (20 Aug 2024)
  
• Antidepressant-Like Effect of Terpineol in an Inflammatory Model of Depression: Involvement of the Cannabinoid System and D2 Dopamine Receptor (20 Aug 2024)
  
• A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid (20 Aug 2024)
  
• Phosphorylation of extracellular signal-regulated kinase as a biomarker for cannabinoid receptor 2 activation (19 Aug 2024)
  
• Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson’s Disease (19 Aug 2024)
  
• Interaction between cannabinoid and nucleotide systems as a new mechanism of signaling in retinal cell death (19 Aug 2024)
  
• Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System (19 Aug 2024)
  
• Cannabinoid Ligands Targeting TRP Channels (19 Aug 2024)
  
• Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study (19 Aug 2024)
  
• Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis (19 Aug 2024)
  
• Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders (18 Aug 2024)
  
• Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans (18 Aug 2024)
  
• Orexin Receptor Multimerization versus Functional Interactions: Neuropharmacological Implications for Opioid and Cannabinoid Signalling and Pharmacogenetics (18 Aug 2024)
  
• Modulation of breast cancer cell viability by a cannabinoid receptor 2 (18 Aug 2024)
  
• Effect of interaction between acute administration of morphine and cannabinoid compounds on spontaneous excitatory and inhibitory postsynaptic currents of magnocellular neurons of supraoptic nucleus (18 Aug 2024)
  
• Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis (18 Aug 2024)
  
• Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System (18 Aug 2024)
  
• Cannabinoid receptor type-1: breaking the dogmas (18 Aug 2024)
  
• Cannabinoid Modulation of the Stressed Hippocampus (18 Aug 2024)
  
• Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes (18 Aug 2024)
  
• Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation (12 Aug 2024)
  
• Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder (12 Aug 2024)
  
• N-Methyl-D-aspartate (NMDA) and cannabinoid CB2 receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA rece (13 May 2024)
  
• Cannabinoids in Medicine: A Multifaceted Exploration of Types, Therapeutic Applications, and Emerging Opportunities in Neurodegenerative Diseases and Cancer Therapy (13 May 2024)
  
• Endocannabinoid System: Chemical Characteristics and Biological Activity (27 Feb 2023)
  
• Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review (27 Feb 2023)
  
• Beyond Pain Relief: A Review on Cannabidiol Potential in Medical Therapies (27 Feb 2023)
  
• Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells (27 Nov 2022)
  
• The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells (05 Sep 2022)
  
• The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies (05 Sep 2022)
  
• Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors? (05 Sep 2022)
  
• Kahweol, a natural diterpene from coffee, induces peripheral antinociception by endocannabinoid system activation (05 Sep 2022)
  
• CB2 Receptor Involvement in the Treatment of Substance Use Disorders (05 Sep 2022)
  
• N-Methyl-D-aspartate (NMDA) and cannabinoid CB2 receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA receptors (01 Sep 2022)
  
• Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses (01 Sep 2022)
  
• Identification of Novel Antagonists Targeting Cannabinoid Receptor 2 Using a Multi-Step Virtual Screening Strategy (01 Sep 2022)
  
• CB2 Receptor in Microglia: The Guardian of Self-Control (01 Sep 2022)
  
• Reviewing the Role of the Endocannabinoid System in the Pathophysiology of Depression (27 Aug 2022)
  
• New Insights in the Involvement of the Endocannabinoid System and Natural Cannabinoids in Nicotine Dependence (27 Aug 2022)
  
• Cannabinoids in Medicine: Cancer, Immunity, and Microbial Diseases (27 Aug 2022)
  
• 1,2,3-Triazole derivatives as highly selective cannabinoid receptor type 2 (CB2) agonists (27 Aug 2022)
  
• Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition (13 Aug 2022)
  
• Cannabinoids in Chronic Pain: Therapeutic Potential Through Microglia Modulation (13 Aug 2022)
  
• The Dynamic Role of Microglia and the Endocannabinoid System in Neuroinflammation (05 Aug 2022)
  
• Targeting the Endocannabinoidome in Pancreatic Cancer (05 Aug 2022)
  
• Endocannabinoid-Mediated Control of Neural Circuit Excitability and Epileptic Seizures (05 Aug 2022)
  
• Chronic Pain and the Endocannabinoid System: Smart Lipids – A Novel Therapeutic Option? (05 Aug 2022)
  
• Cannabinoids, their cellular receptors, and effects on the invasive phenotype of carcinoma and metastasis (05 Aug 2022)
  
• Medical Cannabis Activity Against Inflammation: Active Compounds and Modes of Action (31 Jul 2022)
  
• Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review (31 Jul 2022)
  
• Endocannabinoid Modulation in Neurodegenerative Diseases: In Pursuit of Certainty (31 Jul 2022)
  
• Effects of Cannabidiol on Locomotor Activity (31 Jul 2022)
  
• Cannabinoids for the Treatment of Dermatologic Conditions (31 Jul 2022)
  
• A critical review of cannabis in medicine and dentistry: A look back and the path forward (31 Jul 2022)
  
• Endothelial dysfunction and angiogenesis: what is missing from COVID-19 and cannabidiol story? - Journal of Cannabis Research (26 Jul 2022)
  
• CBD-enriched cannabis for autism spectrum disorder: an experience of a single center in Turkey and reviews of the literature - Journal of Cannabis Research (26 Jul 2022)
  
• A nutraceutical product, extracted from Cannabis sativa, modulates voltage-gated sodium channel function - Journal of Cannabis Research (26 Jul 2022)
  
• Endocannabinoid System and Migraine Pain: An Update (25 Jul 2022)
  
• Combination of cannabidiol with low‑dose naltrexone increases the anticancer action of chemotherapy in vitro and in vivo (25 Jul 2022)
  
• Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease – A Systematic Review (21 Jul 2022)
  
• Endocannabinoid Discovery Timeline (21 Jul 2022)
  
• Coffee & Cannabis (21 Jul 2022)
  
• CBD & the Psychedelic Receptor (21 Jul 2022)
  
• CBD & Cannabis for Endometriosis (21 Jul 2022)
  
• Caffeine, ADHD & the CB1 Receptor (21 Jul 2022)
  
• Cannabinoids: The Science Behind Medical Cannabis (20 Jul 2022)
  
• Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease (20 Jul 2022)
  
• What Is CBC Oil Good For? Benefits, Uses, & Effects (18 Jul 2022)
  
• The Role of Cannabinoid Receptors (18 Jul 2022)
  
• Endocannabinoid System (18 Jul 2022)
  
• Cresco Labs (18 Jul 2022)