Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses

Walsh, Kenneth B., Department Of Pharmacology, Physiology, Neuroscience, School Of Medicine, University Of South Carolina, United States, Mckinney, Amanda E.

As described for the endocannabinoids, the overall pharmacological action of the minor cannabinoids often results from binding at both cannabinoid and “off target” receptors. Although CBN is not as potent an appetite stimulant as Δ9-THC, CBN administration is not associated with the psychotropic effects of Δ9-THC. While clinical trials have not been reported, CBDA may be more effective than CBD in reducing seizures in humans. Potential therapeutic uses of phytocannabinoids. Evidence that the Plant Cannabinoid delta9-tetrahydrocannabivarin Is a Cannabinoid CB1 and CB2 Receptor Antagonist.

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