The effects of UV-PFD (μmol⋅m–2⋅s–1) applied during the flowering stage on aboveground tissue moisture content (%), stem dry weight (DW; g⋅m–2), and cannabinoid and terpene concentra...
Similarly, no statistically significant result was found regarding the strength of CBD used, suggesting that there is not a dose-dependent relationship with N-back performance. Salie...
The structural stability and chemical reactivity properties of the semi-rigid NMP compounds are calculated by using Density Functional Theory (DFT). Finally, molecular docking calcul...
What are cannabinoids? 3.1.4 Medical marijuana and pregnancy Marijuana is the most widely used drug during pregnancy [43]. 5.1 Retrograde cannabinoid signaling, behavior, and neurona...
Cancer, as a mysterious and complex disease, has a multi-stage molecular process that uses the cellular molecular machine and multiple signaling pathways to its advantage. Cannabinoi...
Although, some results suggest that certain effects of cannabinoids are not regulated by CB1 or CB2 (Brown, 2007), which has generated some debate regarding the potential existence o...
Indeed, several studies have revealed the health risks of using these devices, as well as traditional cigarettes and any other tobacco product [ 26 29 ]. On the contrary, more recent...
These results demonstrate that GSE supplementation inhibits trigeminal pain signaling in an injury-free model of migraine-like pain via activation of endocannabinoid receptors and re...
The sprayed aerial parts were evaluated based on phenolic (TPC) and flavonoids (TFC) contents, antioxidant capacity (by FRAP and DPPH assay), photosynthetic pigments including chloro...
Fertilized flowers are considerably less potent, likely due to changes in the contents of phytocannabinoids and terpenoids; therefore, this study examined the effect of fertilization...
Although THC is a weak partial agonist of CBand CB, as far as the stress response is concerned, THC appears to act as a competitive inhibitor of AEA and 2-AG at CB, and THC increases...
However, still little is known whether prenatal MAM exposure could affect ECS signaling in the early postnatal days. A total of 20 males from each group (i.e., CNT and MAM, maximum o...
The CBR2 is mainly found on the surfaces of immune cell types, though its expression has also been observed in the CNS [ 31 ]. THC, CBD, and R(+)-methanandamide have been shown to st...
With hemp balm, the content of CBDA amounted to 44.7–80.4 mg/g of the product, CBD amounted to 7.6–13.8 mg/g, while CBGA and CBG were present in considerably lower concentrations, 2....
This copolymer is named CS-PMMA30, where 30 represents the relative PMMA weight content in the copolymer (%PMMA), as determined by proton-nuclear magnetic resonance (1H-NMR, see belo...
Plasmids contain genes to express resistance to antibiotics. When a biofilm forms, bacterial cells acquire 10–1000 times more resistance to antibiotics [ 46 ]. The oral administratio...
The cannabinoid receptor 2 (CB2 receptor) has attracted considerable interest, mainly due to its potential as a target for therapeutics for treating various diseases that have a neur...
The legal Cannabis industry heavily markets products to consumers based on widely used labeling systems purported to predict the effects of different “strains.” We analyzed the canna...
These data showed how derivate JZL195 determines antinociceptive effects through CB 1 receptors [1 (30 mg/kg), a selective FAAH inhibitor URB597 (IC 50 r FAAH = 33 nM) (reported in 1...
In both references, topping generated a higher number of side shoots, thus more top terminal inflorescence biomass than the control plants (not pruned). The significantly higher biom...
Two major cannabinoids of cannabis, namely cannabidiol (CBD) and tetrahydrocannabinol (THC) have been reportedly used as alternative medicine for diabetes treatment in both pre-clini...
19,35,78,83,200,14,87,107,117,156,167,169,26,44,46,71,72, A formidable challenge is gauging the intake of cannabinoids, as the dosages and potency of different cannabinoid preparatio...
Results: Many studies have demonstrated that endocannabinoids (eCBs) and cannabinoid receptors (CBRs) are expressed in bone and synovial tissues, playing important roles in bone meta...
2-AG activates both CB1R and CB2R. Pain 162, S1–S2. Pain 154, 160–174. Activation of dorsal horn cannabinoid CB2R receptor suppresses the expression of P2Y12 and P2Y13 receptors in n...
Recent research on the use of Cannabis in the medical field has highlighted the possible presence of an entourage effect between terpenes and cannabinoids, which could explain the ob...