G protein-coupled receptor

• Control of glutamate release by complexes of adenosine and cannabinoid receptors (24 Sep 2024)
  
• Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP (02 Sep 2024)
  
• Interaction of Synthetic Cannabinoid Receptor Agonists with Cannabinoid Receptor I: Insights into Activation Molecular Mechanism (02 Sep 2024)
  
• Hexahydrocannabinol (HHC) and Δ9-tetrahydrocannabinol (Δ9-THC) driven activation of cannabinoid receptor 1 results in biased intracellular signaling (02 Sep 2024)
  
• Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists (02 Sep 2024)
  
• Exploring the Therapeutic Potential of Cannabinoid Receptor Antagonists in Inflammation, Diabetes Mellitus, and Obesity (02 Sep 2024)
  
• Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors (02 Sep 2024)
  
• Cannabinoid and Orexigenic Systems Interplay as a New Focus of Research in Alzheimer’s Disease (02 Sep 2024)
  
• A Humanized CB1R Yeast Biosensor Enables Facile Screening of Cannabinoid Compounds (02 Sep 2024)
  
• Distinct activation mechanisms regulate subtype selectivity of Cannabinoid receptors (30 Aug 2024)
  
• Structural basis of selective cannabinoid CB2 receptor activation (29 Aug 2024)
  
• In situ visualization of opioid and cannabinoid drug effects using phosphosite-specific GPCR antibodies (29 Aug 2024)
  
• Understanding the Dynamics of the Structural States of Cannabinoid Receptors and the Role of Different Modulators (28 Aug 2024)
  
• New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 (28 Aug 2024)
  
• Voltage dependence of the cannabinoid CB1 receptor (27 Aug 2024)
  
• A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination (25 Aug 2024)
  
• The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors (21 Aug 2024)
  
• Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death (21 Aug 2024)
  
• MD Simulations Revealing Special Activation Mechanism of Cannabinoid Receptor 1 (21 Aug 2024)
  
• Protein Interactors and Trafficking Pathways That Regulate the Cannabinoid Type 1 Receptor (CB1R) (20 Aug 2024)
  
• Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity (20 Aug 2024)
  
• Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases (20 Aug 2024)
  
• Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity (19 Aug 2024)
  
• Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study (19 Aug 2024)
  
• Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders (18 Aug 2024)
  
• Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans (18 Aug 2024)
  
• Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System (18 Aug 2024)
  
• The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons (12 Aug 2024)
  
• Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation (05 Sep 2022)
  
• Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses (01 Sep 2022)
  
• Identification of Novel Antagonists Targeting Cannabinoid Receptor 2 Using a Multi-Step Virtual Screening Strategy (01 Sep 2022)
  
• Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition (13 Aug 2022)
  
• CBD & the Psychedelic Receptor (21 Jul 2022)
  
• Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease (20 Jul 2022)