Biotechnology

• The Cannabis Proteome Draft Map Project (30 Sep 2024)
  
• Sequence and annotation of 42 cannabis genomes reveals extensive copy number variation in cannabinoid synthesis and pathogen resistance genes (24 Sep 2024)
  
• A Single Nucleotide Polymorphism assay sheds light on the extent and distribution of genetic diversity, population structure and functional basis of key traits in cultivated North American Cannabis (23 Sep 2024)
  
• The synthetic cannabinoid 5-fluoro ABICA upregulates angiogenic markers and stimulates tube formation in human brain microvascular endothelial cells (02 Sep 2024)
  
• The Implications of Cannabinoid-Induced Metabolic Dysregulation for Cellular Differentiation and Growth (02 Sep 2024)
  
• Perturbation of 3D nuclear architecture, epigenomic dysregulation and aging, and cannabinoid synaptopathy reconfigures conceptualization of cannabinoid pathophysiology: part 1–aging and epigenomics (02 Sep 2024)
  
• Perturbation of 3D nuclear architecture, epigenomic aging and dysregulation, and cannabinoid synaptopathy reconfigures conceptualization of cannabinoid pathophysiology: part 2—Metabolome, immunome, synaptome (02 Sep 2024)
  
• Fenofibrate Recognition and Gq Protein Coupling Mechanisms of the Human Cannabinoid Receptor CB1 (02 Sep 2024)
  
• Determination of the Cannabinoid CB1 Receptor’s Positive Allosteric Modulator Binding Site through Mutagenesis Studies (02 Sep 2024)
  
• Cannabinoid receptors type 2: Function and development in agonist discovery from synthetic and natural sources with applications for the therapy of osteoporosis (02 Sep 2024)
  
• Bioengineering of the Marine Diatom Phaeodactylum tricornutum with Cannabis Genes Enables the Production of the Cannabinoid Precursor, Olivetolic Acid (02 Sep 2024)
  
• Overexpression of cannabinoid receptor 2 is associated with human breast cancer proliferation, apoptosis, chemosensitivity and prognosis via the PI3K/Akt/mTOR signaling pathway (30 Aug 2024)
  
• Identification of histone acetyltransferase genes responsible for cannabinoid synthesis in hemp (29 Aug 2024)
  
• Hormonal control of promoter activities of Cannabis sativa prenyltransferase 1 and 4 and salicylic acid mediated regulation of cannabinoid biosynthesis (29 Aug 2024)
  
• Cannabinoid WIN55,212-2 reprograms monocytes and macrophages to inhibit LPS-induced inflammation (29 Aug 2024)
  
• Cannabinoid compounds in combination with curcumin and piperine display an anti-tumorigenic effect against colon cancer cells (29 Aug 2024)
  
• AS1/MMP25 interaction reduces neutrophil infiltration and intestinal epithelial injury in HIV/SIV infection (29 Aug 2024)
  
• Cannabinoid Biosynthesis Using Noncanonical Cannabinoid Synthases (28 Aug 2024)
  
• Molecular Insights into Epigenetics and Cannabinoid Receptors (27 Aug 2024)
  
• Metabolic Engineering of Nicotiana benthamiana to Produce Cannabinoid Precursors and Their Analogues (27 Aug 2024)
  
• Characterization and expression analysis of MATEs in Cannabis sativa L. reveals genes involving in cannabinoid synthesis (27 Aug 2024)
  
• Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica (27 Aug 2024)
  
• In planta Female Flower Agroinfiltration Alters the Cannabinoid Composition in Industrial Hemp (Cannabis sativa L.) (25 Aug 2024)
  
• Delineating genetic regulation of cannabinoid biosynthesis during female flower development in Cannabis sativa (25 Aug 2024)
  
• The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors (21 Aug 2024)
  
• Identification of Novel Cannabinoid CB2 Receptor Agonists from Botanical Compounds and Preliminary Evaluation of Their Anti-Osteoporotic Effects (21 Aug 2024)
  
• Protein Interactors and Trafficking Pathways That Regulate the Cannabinoid Type 1 Receptor (CB1R) (20 Aug 2024)
  
• Manipulation of Cannabinoid Biosynthesis via Transient RNAi Expression (20 Aug 2024)
  
• Identification and Characterization of Cannabimovone, a Cannabinoid from Cannabis sativa, as a Novel PPARγ Agonist via a Combined Computational and Functional Study (20 Aug 2024)
  
• Cannabinoids and Cannabinoid Receptors: The Story so Far (20 Aug 2024)
  
• Analysis of Sequence Variability and Transcriptional Profile of Cannabinoid synthase Genes in Cannabis sativa L. Chemotypes with a Focus on Cannabichromenic acid synthase (20 Aug 2024)
  
• An extreme-phenotype genome‐wide association study identifies candidate cannabinoid pathway genes in Cannabis (20 Aug 2024)
  
• MicroRNA-29a Attenuates Diabetic Glomerular Injury through Modulating Cannabinoid Receptor 1 Signaling (19 Aug 2024)
  
• Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans (18 Aug 2024)
  
• Biotechnological Fungal Platforms for the Production of Biosynthetic Cannabinoids (27 Feb 2023)
  
• Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation (05 Sep 2022)
  
• The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells (05 Sep 2022)
  
• The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies (05 Sep 2022)
  
• Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells (05 Sep 2022)
  
• The Role of Cannabinoids in Bone Metabolism: A New Perspective for Bone Disorders (01 Sep 2022)
  
• N-Methyl-D-aspartate (NMDA) and cannabinoid CB2 receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA receptors (01 Sep 2022)
  
• Identification of Novel Antagonists Targeting Cannabinoid Receptor 2 Using a Multi-Step Virtual Screening Strategy (01 Sep 2022)
  
• Gene Expression Data Mining Reveals the Involvement of GPR55 and Its Endogenous Ligands in Immune Response, Cancer, and Differentiation (01 Sep 2022)
  
• Endocannabinoid Metabolism and Traumatic Brain Injury (01 Sep 2022)
  
• CB2 Receptor in Microglia: The Guardian of Self-Control (01 Sep 2022)
  
• The strengths and limits of cannabinoids and their receptors in cancer: Insights into the role of tumorigenesis-underlying mechanisms and therapeutic aspects (27 Aug 2022)
  
• 1,2,3-Triazole derivatives as highly selective cannabinoid receptor type 2 (CB2) agonists (27 Aug 2022)
  
• Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition (13 Aug 2022)
  
• α-Glucosidase inhibitory activity of cannabidiol, tetrahydrocannabinol and standardized cannabinoid extracts from Cannabis sativa (13 Aug 2022)
  
• Cannabinoids in Chronic Pain: Therapeutic Potential Through Microglia Modulation (13 Aug 2022)
  
• The Dynamic Role of Microglia and the Endocannabinoid System in Neuroinflammation (05 Aug 2022)
  
• Targeting the Endocannabinoidome in Pancreatic Cancer (05 Aug 2022)
  
• Cannabinoids, their cellular receptors, and effects on the invasive phenotype of carcinoma and metastasis (05 Aug 2022)
  
• Cannabinoids Reduce Extracellular Vesicle Release from HIV-1 Infected Myeloid Cells and Inhibit Viral Transcription (05 Aug 2022)
  
• Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis (05 Aug 2022)
  
• A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic Cancer Cells (05 Aug 2022)
  
• Medical Cannabis Activity Against Inflammation: Active Compounds and Modes of Action (31 Jul 2022)
  
• Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review (31 Jul 2022)
  
• Involvement of the endocannabinoid system in the inhibition of Sindbis virus replication: a preliminary study - Journal of Cannabis Research (26 Jul 2022)
  
• Distribution of cannabinoid synthase genes in non-Cannabis organisms - Journal of Cannabis Research (26 Jul 2022)
  
• Combination of cannabidiol with low‑dose naltrexone increases the anticancer action of chemotherapy in vitro and in vivo (25 Jul 2022)
  
• Cannabinoids and COVID-19 (25 Jul 2022)
  
• Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease – A Systematic Review (21 Jul 2022)
  
• Endocannabinoid Discovery Timeline (21 Jul 2022)
  
• Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease (20 Jul 2022)
  
• New molecules derived from cannabidiol are designed with more potent antioxidants (18 Jul 2022)
  
• Kashanchi and Liotta studying effect of cannabidiol on exosome release (18 Jul 2022)
  
• Cannabis-Derived Lignanamides: Potential Candidates for the Treatment of Multidrug-Resistant Cancers (18 Jul 2022)