Transgenic animal models do not express all the factors present in the human disease, including pathological changes and disease progression; they also do not reflect the etiology of...
In addition, given that α-glucosidase inhibitors including CBD would have to survive gastrointestinal tract digestion to exert their desired inhibitory effects on α-glucosidase, the ...
Angiogenesis and endothelial dysfunction in COVID-19 Recently, upon our review research on the role of angiogenesis and endothelial dysfunction in COVID-19 (Norooznezhad and Mansour...
Supplementary Table 1 presents the measured floral cannabinoid concentrations of the immature flower tissues from control plants (day 1) and stress-treated plant (day 6 or day 8) tha...
Study Design Participants completed two treatment sessions involving the oral administration of CBD (300 mg) or a placebo in a randomised, double-blind, crossover design. Each sessi...
THC and CBD are the main cannabinoids that have gained most of the attention. THCA synthase is the enzyme responsible for the production of THCA; CBDA synthase is the enzyme responsi...
Most participants (83%) also reported consuming delta-9-THC cannabis and products and reported substitution for delta-9-THC (57%) and pharmaceutical drugs (59%). Participants’ respon...
CBD causes sex-dependent effects on contextual fear memory and extinction but citalopram does not affect either memory We previously found that CBD enhances contextual memory and it...
The main improvements of the treatment were as follows: a decrease in behavioral problems was reported in 10 patients (32.2%), an increase in expressive language was reported in 7 pa...
Ultimately, 25 studies (Ahmed et al. 2015; Balash et al. 2017; Bruce et al. 2018; Carroll et al. 2004; Chagas et al. 2014a; Chagas et al. 2014b; Consroe et al. 1991; Curtis et al. 20...
Regarding polymorphism in general, it can be seen in Fig. This search was conducted not only on the large number of publications captured under “cannabinoids” in general but also the...
This retrospective study explored the use of CBD-rich products in a medical cannabis clinical setting in Canada and associated effectiveness on a common symptom cluster presentation ...
A follow-up study demonstrated that this mechanism of HU-331 also works against the other human isoform of topoisomerase II, TOP2B (Wilson et al. 2018). These results indicate that H...
Our group settled six formulations combining CBD and terpenes purified from Cannabis sativa L, Origanum vulgare , and Thymus mastichina . CBD is a partial agonist for ...
The results show that cannflavin A concentrations ranging from 2.5 to 50 μM do not induce significant cytotoxicity compared to their vehicle control, while known chemotherapeutic tre...
Many clinically effective anticonvulsants inhibit Na V channels, and purified CBD non-selectively inhibits these channels (Ghovanloo et al. 2018). Our study shows that a CBD-dominant...
The response RSD for each pesticide at its LOQ level in the hemp matrix was less than 20%. 1 a Overlay of the response of blank hemp matrix (red) and propiconazole (green) at a level...
The Internet is a frequent source for information, including for those seeking information on the medical use of cannabis (Kruger et al. 2020b). The current study found that informat...
One analysis provided a breakdown of this collective funding by country, finding that more than $1.4 billion funded researchers in the USA; the UK at $39.9 million, and Canada at $36...
At the same time, SCD allows us to detect compounds that contain sulfur very easily. Indeed, as we analyzed many datasets, we found that the compounds present in the SCD data and the...
In probing astrocytes to understand the biological effects of cannabis, the researchers take a novel approach as earlier studies have focused primarily on neurons.” “One might imagi...
Early studies have shown that some cannabinoids can slow the growth of gram-positive bacteria, such as S. aureus, but not gram-negative bacteria, such as E. coli. Eric Brown, a mic...
Specifically, in this research we acquired hyperspectral images from freshly harvested leaf and flower materials of five cultivars of CBD hemp at five growth stages using a benchtop ...
Getting to this point has meant developing a new manufacturing process that overcomes many of the challenges associated with plant-based extraction, a cornerstone of large-scale cann...
Speaking to Christian Carlsen, Business Director of NNE and Morten Allesoe, Principal Consultant at NNE, Medical Cannabis Network gains an insight into the importance of achieving ca...