This cannabinoid displayed significant therapeutic potential for the treatment of neurodegenerative diseases, such as AD. In 2018, Navarro and co-workers investigated the expression ...
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Under a Creative Commons license open access Abstract Background Exposure to Δ9-tetrahydrocannabinol (THC) is an established risk factor for later-life neuropsychiatric vulnerabi...
[Google Scholar] [CrossRef] [PubMed] Martin, A.B. [Google Scholar] [CrossRef] [PubMed] Klein, T.W. [Google Scholar] [CrossRef] [PubMed] Schatz, A.R. Brain cannabinoid receptor 2: ...
Through this biphasic effect, the increased potency and concentration of THC products may lead to increased levels of maternal stress and anxiety, which may also impact fetal well-be...
Pain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The p...
Background Individuals with schizophrenia are at elevated genetic risks for comorbid cannabis use, and often experience exacerbations of cognitive and psychotic symptoms when expose...
General structural information for cannabinoid metabolites with oxygen at C-11 site. Considering the rapid change in the illicit drug market, a concise synthetic route ( ) where the ...
These data confirm that SM has antioxidant properties in epidermal cells. SM Reduced ROS on UVA/B+Urban-Dust-Stressed RHEs ROS were quantified in the RHEs in order to evaluate the o...
Since its discovery in 1940, through catalytic hydrogenation of THC and cannabinoid derivatives, hydrogenated cannabinoids have been synthesized; only H4CBD and HHC have been of inte...
In summary, these studies identified a role for the CB2 receptor in food intake through depletion of the receptor and exposure to several diets, which resulted in increased CB2 recep...
Activation of this receptor in animal models demonstrate disease-modifying effects against the process of neurodegeneration, suggesting CB2 receptor is a promising therapeutic target...
The protein concentration in these samples was 0.25–0.5 mM. [PMC free article] [PubMed] [CrossRef] [Google Scholar] d. Yeliseev A.; Gawrisch K. Expression and NMR Structural Studies...
Prevalence of perinatal cannabinoid Use Has the proliferation of nCB contributed to the increased prevalence of perinatal cannabinoid use? The equivocal results of many studies of p...
In this study, we used data from a large prospective cohort study, the Safe Passage Study conducted by the Prenatal Alcohol and SIDS and Stillbirth (PASS) Network, of mother-infant d...
Cardiovascular events are among the risks of cannabis and cannabinoid consumption, as both natural and synthetic cannabinoids induce changes in the cardiovascular system of humans an...
On the one hand, these compounds could selectively bind the CB2 receptor that does not show psychoactive effects and, in glia, has opened new avenues in this field of research, shedd...
Synthetic cannabinoid receptor agonists (SCRAs) constitute the largest and most defiant group of abuse designer drugs. These new psychoactive substances (NPS), developed as unregulat...
Effect of 3-arm antagonists in modulating GRABeCB2.0 fluorescence in presence of 300 nM CP55940. We also tested the antagonists to inhibit agonist fluorescence in the presence of CP5...
Table 1 N Group Disorder Genes identified in the Schrott database Genes implicated % Genes implicated in Schrott Reference 1Brain disordersSchizophrenia59768587.10%Trubetskoy V. Nat...
Mitochondria have over 1,000 different proteins. In general terms, these effects occur either because of lactate as a metabolic substrate, via lactate signaling, or from lactylation ...
Of all physicians contacted, 43 physicians indicated that they treated patients with cannabinoids and were interested in inviting them to participate in the study. TABLE 3 4 Discuss...
Conclusion The cannabinoid extract (THC:CBD) was an appropriate adjuvant agent to reduce CINV in patients with gynecologic cancer who received high-emetogenic chemotherapy. All part...
Inflorescences of medicinal cannabis are used worldwide for their medicinal properties for various medical conditions such as cancer, pain management, and rheumatic diseases [1–3]. I...
Pre-Processing Techniques for NIR Spectra In the context of cannabinoid prediction using near-infrared (NIR) spectroscopy, pre-processing techniques, such as standard normal variate...