There is evidence that also other non-CB1R and non-CB2R (GPR18, GPR119, and GPR55) are involved in the signaling of the ECS [18]. AEA and 2-AG can also activate other receptors, such...
60 Cannabinoids have been shown to have varying effects on the ability of tumors to establish a metastasis, although from much of the data it is unclear at which stage of metastasis ...
The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/cells11040723/s1 , Figure S1: Cell viability analysis of CBD on HIV-1 infected monocyt...
Low‐quality evidence from both RCTs and NRSIs shows no significant benefits of cannabinoids for weight gain, appetite stimulation, and better quality of life, three important outcome...
Given the inhibitory effects of THC:CBD on TLR3 signalling to CXCL10 and IFN-β in PBMCs, in addition to evidence linking TLR4 to MS pathogenesis [ 15 16 ], we next set out to determi...
The measurements were done on five plants per breeding population (N = 5). Photosynthetic Parameters Most photosynthetic parameters differed significantly between breeding populatio...
A total of 2 different extraction procedures were performed according to previous published studies [ 30 32 ] to obtain medical Cannabis oil 1 (MCO-1) and MCO-2 (SIFAP and Calvi meth...
The uniqueness of CIK cells is their encouraging synergetic effect with cancer associated inhibitors/compounds in preclinical models since cannabinoids have been the subject of inten...
When dissociated spleen cells were placed in culture ex vivo and stimulated with C3HeB/FeJ cells in an MLR, the cells from the O-1966 treated mice were significantly suppressed in th...
The applications of plants as medicines predates human history. One notable medicinal plant that has continued to garner attention over the years, and in recent times, is Cannabis s...
Blood coagulation disorders or coagulopathies are a group of disorders in which there is a hypercoagulative state leading to excessive abnormal blood clot formation and tissue ischem...
Usage sessions included real-time subjective changes in fatigue intensity levels prior to and following Cannabis consumption, Cannabis flower characteristics (labeled phenotype, cann...
Cannabis sativa is a quantitative short-day plant where decreasing daylength (often) regulates flowering initiation (van der Werf et al., 1994). Some studies reported that shorter ph...
Altered transcripts following THC exposure were found in a substantial number of genes linked to autism (80 genes) and intellectual disability (167 genes), with fewer overlapping wit...
The legalization of cannabis in many countries, as well as the decrease in perceived risks of cannabis, have contributed to the increase in cannabis use medicinally and recreationall...
Keywords: cannabis; dermatology; new modality of treatment; anti-inflammatory; topical usage. FIGURE 1: Benefits of cannabidiol for your skin.9 Sebaceous gland related disorders Acn...
The aim of this study was two-fold: (1) determine whether CBD/CBDA rich hemp extract can help control canine refractory epileptic seizure patients who are only partially responsive t...
Cannabinoid type 2 receptor signaling. The involvement of CB2Rs in ALS has been demonstrated by different studies. Brain cannabinoid CB2 receptors modulate cocaine’s actions in mice....
In the prediction of total THC content, RPD values > 2 were obtained, which indicates the goodness of the models. The best model to predict CBD content was also obtained without a...
Cannabinoids are the active medicinal constituents against the development of numerous conditions. Then these naturally cannebinoids acids are converted via decarboxylation, which re...
Cannabis sativa L. has a wide range of therapeutic applications against several diseases, and many review articles have detailed its chemistry [ C. sativa L. in addition to Δ9-THC in...
In the veterinary medicine, therapeutic applications of CBD in dogs include osteoarthritis-associated pain (6, 25, 26), aggressive behavior (27), and epilepsy (7, 28). We hypothesize...
The hemp plant consists of the woody part (44% of the plant weight), fibres (24%), seeds (11%) and other components such as flowers, leaves and dust (21%) [ 1 3 ]. Since each part of...
Most patient access, however, is through the Special Access Scheme Category B (SAS-B) which allows practitioners to make an application to the TGA to allow an individual patient to b...
As medicinal cannabis related clinical research has predominately focused on CNS-related diseases, such as neurodegeneration and neurological disorders, pain, substance use disorders...