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    The attitudes, knowledge and confidence of healthcare professionals about cannabis-based products

    Keywords: Healthcare professional education, Survey, Cannabis, Cannabinoids, Cannabis-based product, Cannabis-based medicine Introduction Cannabis refers to the Cannabis sativa L p...


    Lessons for cannabinoid regulation from electronic nicotine delivery system product regulation

    A recent third-party review by the Reagan-Udall Foundation was critical of FDA for its lack of transparency—finding that application requirements are “vague and frequently changing” ...


    Introduction to the special issue: the two sides of hemp: medical and industrial

    Clear and consistent regulations are essential to support the growth of the hemp industry while ensuring consumer safety and compliance with the law. Studies conducted in the early 1...


    Hypothalamic cannabinoid signaling: Consequences for eating behavior

    Neuron. Neuron. Neuron. Neuron. Neuron.


    Examining the moderating role of cannabis use on the relationship between alcohol consumption and inflammation in individuals with alcohol use disorder

    Keywords: alcohol and cannabis co‐use, IL‐6, inflammation The relationship between circulating IL‐6 levels, alcohol consumption, and cannabis use was assessed in individuals with an...


    Efficacy of cannabinoids compared to the current standard treatments on symptom relief in persons with multiple sclerosis (CANSEP trial): study protocol for a randomized clinical trial

    1.2 Study objectives The main aims of this study are: (1) to compare the efficacy of THC and CBD, alone and in combination, as add-on therapies to the current standard treatments fo...


    Editorial: Plant nutrition and biostimulants: regulators of secondary metabolites and crop productivity in both normal and abiotic stress conditions

    Therefore, within this Research Topic, efforts have been made to improve our understanding of the mechanisms related to the role of plant nutrients and biostimulants on plant product...


    Diet supplementation with hemp (Cannabis sativa L.) inflorescences: effects on quanti

    Conjugated linoleic acids alter milk fatty acid composition and inhibit milk fat secretion in dairy cows. [CrossRef] [Google Scholar] Mierlita D. 2016. [CrossRef] [Google Scholar] ...


    Comparison of decarboxylation rates of acidic cannabinoids between secretory cavity contents and air-dried inflorescence extracts in Cannabis sativa cv. ‘Cherry Wine’

    The major cannabinoid content was determined as follows: CBDA (189.0 ± 68.8 mg/L), CBD (1.90 ± 0.7 mg/L), THCA (14.2 ± 5.4 mg/L), CBCA (9.3 ± 3.1 mg/L), CBGA (3.0 ± 1.5 mg/L), and CB...


    Comparing CB1 receptor GIRK channel responses to receptor internalization using a kinetic imaging assay

    Keywords: Cannabinoid receptor, Cannabinoid, G protein-coupled receptor, Receptor trafficking, Receptor signaling, Real-time assay Subject terms: Pharmacology, Molecular neuroscienc...


    Clinical and cognitive outcomes in first-episode psychosis: focus on the interplay between cannabis use and genetic variability in endocannabinoid receptors

    Cannabinoid receptor gene polymorphisms and cognitive performance in patients with schizophrenia and controls. Brain cannabinoid CB2 receptor in schizophrenia. The role of cannabis i...


    CBD oil by-product (Hemp flakes): Evaluation for nutritional composition, heavy metals and functionality as a food ingredient

    Thus, this research aimed to assess the nutritional, safety (heavy metals), and functional (antioxidant properties and cannabinoid content) values of hemp flakes by comparing it with...


    Cannabinoids detected in exhaled breath condensate after cannabis use

    Five different cannabinoids, including Δ9-tetrahydrocannabinol (THC), were detected in EBC collected from cannabis users. THC concentrations in EBC samples collected at 0.7 h showed ...


    Cannabinoids and triple-negative breast cancer treatment

    Immune cells express both CB1R and CB2R (44, 45), although the expression of CB1R is significantly lower compared to CB2R (41, 46). 4 Cells of the TNBC microenvironment and the endoc...


    Cannabinoids and monoaminergic system: implications for learning and memory

    10.1016/j.bbr.2008.03.020 [PubMed] [CrossRef] [Google Scholar] Hansen N. (2017). 10.1017/S0033291704002260 [PubMed] [CrossRef] [Google Scholar] Marsicano G., Lutz B. 10.1016/j.lfs....


    Utilizing derivatizing agents for the differentiation of cannabinoid isomers in complex food, beverage and personal-care product matrices by ambient ionization mass spectrometry

    Recent legalization and decriminalization of marijuana at the state level has not only contributed to a rise in the recreational use of Cannabis sativa, also known simply as Cannabis...


    Unveiling the Potential of Cannabinoids in Multiple Sclerosis and the Dawn of Nano-Cannabinoid Medicine

    Clinical studies on the use of cannabinoids for the management of multiple sclerosis. Treatment of Multiple Sclerosis: A Review. Multiple Sclerosis. Cannabis Cannabinoid. Delta-9-THC...


    Tumor necrosis factor α, and agonist and antagonists of cannabinoid receptor type 1 and type 2 alter the immunophenotype of stem cells from human exfoliated deciduous teeth

    This study shows the interaction between mesenchymal stromal cells and the immune and endocannabinoid systems. Human mesenchymal stem cells modulate allogeneic immune cell responses....


    Trends of emergency department visits for cannabinoid hyperemesis syndrome in Nevada: An interrupted time series analysis

    The State of Nevada legalized cannabis for medical use and recreational use in 2001 and 2016, respectively. Results Trends of CHS ED visits in study population presents trends of o...


    Trends in prescription and cost of Sativex, a cannabinoid-based medicine, in treating patients with multiple sclerosis in England

    Multiple Sclerosis Journal, 10(4), 425–433. Multiple Sclerosis Journal, 16(11), 1349–1359. Journal of Multiple Sclerosis, 1(2), 1–2. Multiple Sclerosis Journal, 16(11), 1349–1359. Mu...


    Therapeutic Potential of Cannabinoid Profiles Identified in Cannabis L. Crops in Peru

    by Pedro Wong-Salgado 1,2,3,* , Fabiano Soares 2,3,4 , Jeel Moya-Salazar 5,* , José F. Ramírez-Méndez 1,3 , Marcia M. Moya-Salazar 3,6 , Alfonso Apesteguía 7 and Americo...


    Therapeutic Application of Modulators of Endogenous Cannabinoid System in Parkinson’s Disease

    Parkinson’s disease. J. Cannabis Res. [Google Scholar] [CrossRef] [PubMed] Santos, N.A.G. [Google Scholar] [CrossRef] [PubMed] Zuardi, A.; Crippa, J.; Hallak, J.; Pinto, J.; Chagas...


    The synthetic cannabinoid 5-fluoro ABICA upregulates angiogenic markers and stimulates tube formation in human brain microvascular endothelial cells

    The culture medium was supplemented with various components in the endothelial cell growth kit (PCS-110-040) from the American Type Culture Collection. Cells were plated on 96-well m...


    The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits

    Regarding the structure, OS ( A) shares a similar structure with AEA (a partial agonist of CB1 receptors) and Org27569 (a positive allosteric modulator of CB1 receptors in binding, a...


    The Relationship between Muscarinic and Cannabinoid Receptors in Neuronal Excitability and Epilepsy: A Review

    Summary Cannabinoids have shown to reduce seizure activity and neuronal excitability in several epileptic models through the activation of muscarinic receptors with drugs which modu...


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