However, such advances in ECs and the introduction of the recent cannabinoid medications are a new pathway for preventing destructive inflammatory reactions such as periodontitis. 4 ...
Furthermore, plant growth data including plant height, SPAD values and green canopy cover were measured every 2 to 3 weeks during crop growth from five randomly selected plants in ea...
Chromosomal location, gene structure, phylogenic tree, conserved motifs and cis-acting elements analysis of CsMATEs Visualization of CsMATEs structures and chromosome locations were...
Despite its historical significance, the “red oil” brought, in addition to the tragedies mentioned above, a great deal of confusion to the cannabis research community during its earl...
Objectives The primary objective of the present study is to understand if cannabinoid supplementation to standard therapy is favorable, in terms of clinical outcome, in IBD patients...
Activated Th2 cells release IL-31 which stimulate itching by acting on IL-31 receptor A (IL-31RA) expressed on sensory nerve fibers and various immune cells, such as MCs, macrophages...
Results Although often presenting with similar symptoms such as abdominal pain and vomiting, cannabinoid hyperemesis syndrome (CHS) and cannabis withdrawal syndrome (CWS) are the re...
Methods For these purposes, we performed a dose-response treatment with CBD by exposing male adult rats to single and repeated CBD treatments at 5, 15 and 30 mg/kg, to investigate b...
The endocannabinoid system, and in particular the cannabinoid CB2 receptors, have been extensively studied, due to their important role in neuroinflammation, especially in microglial...
2.2 Light treatment After adjustment, the plants were subjected to treatment with 4 LED lights (Bisol LED light Co., Seoul, Korea). 2.4 Photosynthetic pigments analysis For the det...
To produce OLA in Y. lipolytica, the plasmid pYLXP’-CsOLS-CsOAC encoding the codon-optimized CsOLS and CsOAC was transformed into Y. lipolytica. Among these chosen hexanoyl-CoA synth...
Similar to CB receptors and other opioid receptors, NOP receptors were associated with the group of G protein-coupled receptors (GPCRs), which regulate adenylate cyclase activity. an...
We tested a panel of five common cannabis terpenoids, myrcene, linalool, limonene, α-pinene and nerolidol, in two neuronal models, autaptic hippocampal neurons and dorsal root gangli...
for mice). Treatment effects of cannabinoid combinations and cannabis extracts in Alzheimer’s disease Research suggests that cannabinoid treatments involving a combination of THC an...
In all skin compartments, CBRs immunoreactivity was observed in the cytoplasm, whereas signals were rarely observed in the nuclei of single cells in the whole skin tissue (Figures 2 ...
The effectiveness of the novel 1,8-naphthyridine-3-carboxamide derivatives and of compound LV62 were determined against neuroblastoma cells. Cell. Cell. ; et al. Synthesis and In Vit...
Under a Creative Commons license open access Highlights • Summarizes research on the effects of cannabinoid drugs on synaptic transmission spanning animal and human research • ...
Of these cannabinoids the cannabis plant produces predominantly cannabidiolic acid (CBDA) and tetrahydrocannabinolic acid (THCA), which during heat extraction becomes decarboxylated ...
Mainly, the rewarding effects of alcohol occurred by the interaction between the opioidergic and dopaminergic mesolimbic systems, involving the increased firing of dopamine neurons i...
Studies reviewed in the previous sections demonstrated the role of CB2Rs in the regulation of physiologic functions and hence they can be utilized as a potential target in neuroinfla...
SampleMoisture Level (wb)Experimental DetailsFindingsSourceInflorescence and leaves of hemp (three varieties: Pipeline, Maverick and Queen Dream CBD)Initial: 75–78%, Final: 9–13%Fre...
Previous studies have reported antioxidant, anti-inflammatory, and antimycotic properties of the certified hemp variety “Futura 75” [42], whose essential oil from inflorescences show...
TABLE 1 Results Radioligand binding When tested alone, the cannabinoids (∆8-THC, ∆6a,10a-THC, 11-OH-∆9-THC, and CBN) reduced [3H]CP55,940 binding to hCB1R to some extent (Figure 2...
In one plot in each enclosure, two UVA LED bars were centered 0.24 m apart, at the same height of the LED Toplight fixtures. Foliar THC concentrations were higher in the UVA + UVB vs...
The gene expression of two cannabinoid pathway genes, CBDAS and THCAS was measured using qRT-PCR (Deguchi et al., 2021). Notably, non-functional sequences present in the hemp genome ...