Quantitative real-time PCR (RT-PCR) gene expression analysis To evaluate gene expression profiles, quantitative real-time PCR (qPCR) was carried out in a CFX96 thermal cycler (Bio-R...
Thus, the aims of the present study were (i) to investigate the taste preference of late-pregnant dairy cows by offering sweet-tasting, umami-tasting and taste-unaltered feed and wat...
As N input is one of the key factors for plant development and function, extensive studies have been focused on the impact of N supply on plant yield (Bouchet et al. Citation2016; Le...
Thus, its mechanism of efficacy, especially against seizure-related disorders, is mainly attributed to targets independent of CB receptors. Articles published in Research Topic A to...
This paper provides a framework for ensuring consistent and quality analysis of such real-world evidence, which can highlight therapeutic potential for further investigation in more ...
To demonstrate feasibility and applicability, we utilized CannaCount to generate estimated maximum THC and CBD exposure in a sample of medical cannabis patients enrolled in a longitu...
Data We systematically screened for sources including a measure of effect of a cannabinoid compound on pain in COP patients that might be treated by our target specialists. Study Se...
The IL-10/TNFα, IL-10/IL-1β and IL-10/IL-6 cytokine ratios were significantly higher in LPS-stimulated WIN-hmoDCs than conventional hmoDCs (Figure 1C), indicating that WIN55,212-2 re...
[Google Scholar] [CrossRef] Liu, L.Y. Expression of cannabinoid receptors in human kidney. Kidney J. Cannabinoid Signaling in Kidney Disease. Cannabinoid Signaling in Kidney Disease...
Cannabinoid receptors, CB1 and CB2, are expressed on both CD4+ and CD8+ T cells and are upregulated upon T cell activation by anti-CD3/CD28 mAb [13,36,37]. [Google Scholar] [CrossRef...
3.1.1 Effect of cannabinoid compounds together with curcumin and piperine on cell survival HT29 and HCT116 colon cancer cell lines were treated with CBD, CBG, curcumin, piperine eit...
However, due to cannabinoids’ unfavorable physicochemical properties and adverse systemic effects, along with ocular biological barriers to local drug administration, drug delivery s...
by Ilias Muhammad 1,* , Mohammad A. Ibrahim 1 , Mallika Kumarihamy 1,† , Janet A. Lambert 1,‡ , Jin Zhang 1 , Marwa H. Mohammad 1,§, Shabana I. Khan 1,2 , David S. Pas...
To determine the role of lncRNAs in HIV/SIV-induced intestinal epithelial dysfunction, we profiled and identified differentially expressed (DE) lncRNAs based on a log2 fold-change (F...
Replication analysis Based on the top identified SNP in this cohort, further replication data was obtained from three datasets: DKD summary results of Biobank Japan32, the FinnGen P...
by Anjela Manandhar 1, Mona H. Haron 2, Michael L. Klein 1 and Khaled Elokely 1,* 1 Institute for Computational Molecular Science and Department of Chemistry, Temple Univer...
However, cannabinoids interact with receptors other than CB1R and CB2R and thus motor development may be impacted through the interactions of eCBs with non-canonical cannabinoid rece...
Cannabis sativa and Cannabis indica versus “Sativa” and “Indica.” In Cannabis sativa L.—Botany and Biotechnology; Chandra, S., Lata, H., ElSohly, M.A., Eds. Cannabis Cannabinoids 201...
Stimulation of the CB2 receptor results in anti-inflammatory effects. The pediatric chronic pain clinic at The Hospital for Sick Children provides interdisciplinary pain management t...
Thus, in addition to molecular tuning, Pc thin films can be morphologically tuned through film engineering by altering the deposition surface, deposition conditions, or post-depositi...
Chemical volatile percentage composition of GEL, SMC, and SCBD of C. sativa pollen samples. Chemical volatile percentage composition of GEL, SMC, and SCBD of C. sativa pollen extract...
Abstract Industrial hemp (Cannabis sativa) cultivars used for flower, fiber, or seed production are usually considered short-day plants and flower in response to photoperiod. In 202...
Materials and Methods: Patients with (episodic migraine; n=29), (CM; n=15), MOH (n=16) and 31 healthy controls were recruited and blood levels of nociceptin and anandamide (AEA) were...
Cell. Cell. Cells 2021, 10, 586. Cell. Cells 2020, 9, 817.
Experiments in cAMP assays highlighted that only JR22a behaves as a CB2R bitopic (dualsteric) ligand. Further, the results support that JR22a interacts with both orthosteric and allo...