Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications
Hebaallah Mamdouh Hashiesh | M.F. Nagoor Meeran | Charu Sharma | Bassem Sadek | Juma Al Kaabi | Shreesh K. Ojha | Hebaallah Mamdouh | M.F. Nagoor | Juma Al | Shreesh K
These effects are mediated via the binding of BCP to CB2R, which activates PGC1-α and promotes the interaction between PPAR-γ and different transcriptional factors, such as PPAR-α leading to increase in the expression of enzymes involved in the oxidation of fatty acids in the liver. Diabet. Diabet. Diabet. Diabet.
Tags:
- GLUT4
- Wound healing
- AMP-activated protein kinase
- Peroxisome proliferator-activated receptor alpha
- Beta cell
- Insulin
- Sterol regulatory element-binding protein
- Kinase
- Cannabinoid receptor 2
- Metabolic dysfunction–associated steatotic liver disease
- Forkhead box protein O1
- Glucose
- Inflammation
- Nutrients
- Biochemistry
- Biology
- Cell biology
- Cellular processes