Single Compound vs. Whole Plant CBD
Byline
A groundbreaking study from Israel has documented the superior therapeutic properties of whole plant CBD-rich cannabis extract as compared to single-molecule cannabidiol (CBD). The Israeli team sought to determine whether the administration of a whole plant CBD-rich extract would also generate a bell-shaped dose-response curve when administered to mice. The Israeli researchers extracted CBD-rich oil from clone 202. Rather than showing a bell-shaped curve, where a therapeutic effect could only be achieved at a certain concentration of pure CBD, the whole plant CBD-rich extract caused a direct, dose-dependent inhibition of pain, inflammation, and TNFa production. “In stark contrast to purified CBD,” the Israeli team reported, “the clone extract…provided a clear correlation between the anti-inflammatory and anti-nociceptive responses and the dose, with increasing responses upon increasing doses, which makes this plant medicine ideal for clinical uses.” Moreover, the Israeli researchers found that a small amount of CBD in the clone extract was needed for significant pain relief compared to the much larger amount of pure CBD required to achieve the same analgesic effect.
Tags:
- Cannabidiol
- Dose (biochemistry)
- Analgesic
- Anti-inflammatory
- Medical cannabis
- Tumor necrosis factor
- Pharmacy
- Clinical medicine
- Medicine
- Health
- Drugs
- Pharmacology
- Medical treatments
- Medical specialties
- Health sciences
- Health care
- Pharmaceutical sciences
- Chemicals in medicine
- Medicinal chemistry
- Therapy
- Diseases and disorders