CB2 Cannabinoid Receptor as a Potential Target in Myocardial Infarction: Exploration of Molecular Pathogenesis and Therapeutic Strategies
Sagar A. More | Rucha S. Deore | Harshal D. Pawar | Charu Sharma | Kartik T. Nakhate | Sumit S. Rathod | Shreesh Ojha | Sameer N. Goyal | Sagar A | Rucha S
The inhibition of CB1 receptors [72] and activation of CB2 receptors [28] retarded cardiac fibrosis following MI and improved the cardiac function. [Google Scholar] [CrossRef] [PubMed] Kaschina, E. Cannabinoid CB1/CB2 Receptors in the Heart: Expression, Regulation, and Function. [Google Scholar] [CrossRef] Pawar, H.D. [Google Scholar] [CrossRef] [PubMed] NOX2-Induced Myocardial Fibrosis and Diastolic Dysfunction: Role of the Endothelium—PubMed. [Google Scholar] [CrossRef] Nakhate, K.T.
Tags:
- NADPH oxidase
- Reperfusion injury
- Inflammation
- Cannabinoid receptor 2
- AMP-activated protein kinase
- Endothelium
- Mothers against decapentaplegic homolog 3
- Transforming growth factor beta
- Tumor necrosis factor
- Reactive oxygen species
- Nitric oxide synthase
- Interleukin 6
- Lactate dehydrogenase
- Ischemia
- Cardiac muscle
- Atherosclerosis
- Autophagy
- Biology
- Biochemistry
- Cell biology