Cannabinoid Receptor Type-2 in B Cells Is Associated with Tumor Immunity in Melanoma
Thomas Gruber | Steve Robatel | Mirela Kremenovic | Lukas Bäriswyl | Jürg Gertsch | Mirjam Schenk
In this study, using data from The Cancer Genome Atlas (TCGA)’s melanoma cohort, human melanoma tissues and murine models, as well as single-cell RNA sequencing, we uncover a critical role of CB2Rs in B cells in cutaneous melanoma. Cell 2000, 101, 455–458. ; et al. IL-32γ potentiates tumor immunity in melanoma. Cell. Cannabinoid Receptor Type-2 in B Cells Is Associated with Tumor Immunity in Melanoma Cancers 13, no.
Tags:
- Cannabinoid receptor 2
- Regulatory T cell
- Melanoma
- Fluorescence in situ hybridization
- Endocannabinoid system
- Tumor microenvironment
- RNA-Seq
- Flow cytometry
- Cancer immunotherapy
- The Cancer Genome Atlas
- Immune system
- Cancer
- Single-cell sequencing
- Health sciences
- Biology
- Medical specialties
- Clinical medicine