Cannabinoid Receptor 1 Agonist ACEA and Cannabinoid Receptor 2 Agonist GW833972A Attenuates Cell-Mediated Immunity by Different Biological Mechanisms
Nuchjira Takheaw | Kanyaruck Jindaphun | Supansa Pata | Witida Laopajon | Watchara Kasinrerk
Cannabinoid receptors, CB1 and CB2, are expressed on both CD4+ and CD8+ T cells and are upregulated upon T cell activation by anti-CD3/CD28 mAb [13,36,37]. [Google Scholar] [CrossRef] Shah, S.A.; Gupta, A.S.; Kumar, P. Emerging role of cannabinoids and synthetic cannabinoid receptor 1/cannabinoid receptor 2 receptor agonists in cancer treatment and chemotherapy-associated cancer management. Cell. Cell. Cells.