Beta-Caryophyllene, a Cannabinoid Receptor Type 2 Selective Agonist, in Emotional and Cognitive Disorders


Caterina Ricardi | Serena Barachini | Giorgio Consoli | Donatella Marazziti | Beatrice Polini | Grazia Chiellini


The involvement of the ECS in modulating psychiatric disorders appears to be due to two G protein-coupled receptors, cannabinoid receptor type-1 (CB1R) and cannabinoid receptor type-2 (CB2R). Beta-Caryophyllene May Be Prospective in the Treatment of Anxiety and Depression Significant findings suggested that BCP may hold clinical value for treating depression and anxiety disorders by addressing both behavioral and inflammatory responses to chronic stress. In another study on Swiss mice, the behavioral effects of oral treatment (50, 100 and 200 mg/kg, p.o.) Brain Cannabinoid Receptor 2: Expression, Function and Modulation. [Google Scholar] [CrossRef] García-Gutiérrez, M.S.

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