The dosing schedule of the placebo oils was such that two placebo doses were administered prior to the start of cannabinoid oil dosing to ascertain tolerability to increasing volumes...
Our results obtained with the Neutral Red test have found that Cannabis sativa L. extract at all tested concentrations (1–1000 μg/mL) showed no cytotoxic effect on keratinocytes and ...
CB2 Receptor Mediates Glucose Uptake in C2C12 Myotubes As we have previously demonstrated that BCP improves glucose uptake in C2C12 muscle cells [23], here, we investigated how this...
The endocannabinoid system (ECS) is natural physiological system in the humans. The presence of the ECS system involves different roles in body. The endocannabinoid system involves r...
In a study of 20 schizophrenia patients, the blood levels of anandamide were shown to be higher in patients with acute schizophrenia compared to healthy controls (26). A first study ...
PLA signals of CB1 and ankB were observed in cultured primary neurons (Fig. Our results clearly showed that the PLA signal located in axons but not in dendrites (Supplementary Fig. O...
Here, we focused mainly on the role of type-1 Cannabinoid Receptor gene (CNR1) gene, which encodes for CB1R, and its regulation in food intake and eating behaviors. Via CB1R, eCBs mo...
Analysis was performed on each of six conditions for four cannabis chemovars: fresh flower, frozen-sifted flower by-product, Kryo-Kief™ dry ice process, dried flower, dried sifted fl...
The chemical structures of some terpenoids produced by Cannabis sativa L. The chemical structures of some flavonoids produced by Cannabis sativa L. Cannabis alkaloids. Plants. Non-Ca...
Sensory preconditioning in particular represents the most common behavioral protocol for studying incidental associations among relatively neutral or low-salience stimuli. Through th...
Natural product isolation and characterization is an especially challenging process involving human creativity along with available resources. Further complicating progress in Cannab...
Chemical Analysis of the Essential Oil of Hemp (Cannabis sativa L.) Briefly, 11 phenotypes from “Carmagnola” selected (CS), “Tiborszallasi” (TS), and “Finola” selection (FS) contain...
Moreover, clinical studies indicate that cannabis consumption during pregnancy leads to fetal growth restriction (FGR), which is associated with an increased risk of obesity, type II...
Mammana et al. started this Special Issue with a research article on the medical use of cannabis products. In their original investigation, Tejedor-Cabrera et al. explored the risk o...
Transient expression systems are widely used as a valuable tool for vector construct evaluation, all the while being fast and inexpensive with specific protocols in cannabis already ...
It is conceivable that allelic variation among CBDA synthases or expression of other cannabinoid synthases could lead to altered CBD:THC ratios. Most studies to date on the effect of...
Further, alcohol consumption has decreased significantly in states with legalized medical cannabis (10), and medical users have been shown to drink less and have fewer alcohol-relate...
Although these industrial hemp genotypes are mainly cultivated for fibre and seed production, however, cannabinoids offer an additional value. At seed maturity (S4), genotype Futura7...
Cannabis Cannabinoids 2020, 1–8. Cannabis Cannabinoids 2018, 1, 19–27. Plant J. Plant J. Plant 2011, 4, 616–625.
The aim of this study was to evaluate the growth performance, such as the plant height, biomass yield, root growth and cannabinoid content, of cannabis plants grown in different subs...
Chemical structure of cannabimovone (CBM) with functional groups colored in red. Therefore, to further explore the pharmacological activity of CBM on PPARγ, we induced 3T3-L1 pre-adi...
CB2 is Detectable by Flow Cytometry on Days 7 and 14 in CIK Cells Initial studies were performed to assess the differential expression of CB2 receptor in the main cell subsets of hu...
However, cannabis plants only produce carboxylated cannabinoids. Optimum temperatures were established for the conversion of 6 cannabinoid acids to their neutral cannabinoid forms. R...
Cannabinoids 2013, 7, 11. Cell. [Google Scholar] [CrossRef] [PubMed] [Green Version] Rieder, S.A.; Chauhan, A.; Singh, U.; Nagarkatti, M.; Nagarkatti, P. Cannabinoid-induced apoptos...
Endocannabinoids in the Hippocampus and the Temporal Neocortex of Patients With Pharmacoresistant Mesial Temporal Lobe Epilepsy The tissue levels of endocannabinoids and OEA in the ...